SCHEMBL18158545

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18158240	0.91	KDR (0.65)	KDRSRCFLT1EPHB2FGFR1
	SCHEMBL18158540	0.91	KDR (0.64)	KDRSRCFLT1EPHB2FGFR1
	SCHEMBL29464032	0.90	EGFR (0.73)	KDRSRCFLT1EPHB2RET
	SCHEMBL30844364	0.90	EGFR (0.73)	KDRSRCFLT1EPHB2RET
	SCHEMBL18153627	0.90	EGFR (0.73)	KDRSRCFLT1EPHB2RET
	Hydrochloric Acid SCHEMBL29360029	0.89	EGFR (0.72)	KDRSRCFLT1EPHB2RET
	Hydrochloric Acid SCHEMBL18153640	0.89	EGFR (0.72)	KDRSRCFLT1EPHB2RET
	SCHEMBL8933814	0.85	KDR (0.88)	KDRSRCFLT1EPHB2FLT4
	Hydrochloric Acid SCHEMBL8808201	0.84	KDR (0.86)	KDRSRCFLT1EPHB2FLT4
	SCHEMBL18158267	0.83	EGFR (0.76)	KDRSRCFLT1EPHB2FGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.