SCHEMBL18158879

SCHEMBL18158879

COCCO[C@H]1C(OP(=O)(O)OC[C@@H]2C[C@H](OCCOC)[C@H](n3cnc4c(N)ncnc43)O2)[C@@H](COP(=O)(O)O)OC1n1cnc2c(N)ncnc21

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ RNASEL Q05823 12/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27062515 0.93 RNASEL (0.56) RNASEL
SCHEMBL27062506 0.92 RNASEL (0.55) RNASEL
SCHEMBL27062475 0.90 P2RY1 (0.60) RNASEL
SCHEMBL27062505 0.86 RNASEL (0.52) RNASEL
SCHEMBL16410912 0.86 RNASEL (0.52) RNASEL
SCHEMBL18158969 0.83 ADORA1 (0.64) RNASEL
SCHEMBL18158888 0.83 P2RY1 (0.52) —
SCHEMBL12963349 0.83 RNASEL (0.70) RNASEL
SCHEMBL7745726 0.83 ADORA1 (0.64) RNASEL
SCHEMBL24703982 0.83 RNASEL (0.75) RNASEL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016168592-A2 COMPOSITIONS FOR MODULATING C9ORF72 EXPRESSION IONIS PHARMACEUTICALS, INC. (US) 2016-10-20 — — WO disclosed
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