Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 14/20 | 0.76 |
| ▸ | ALK | Q9UM73 | 14/20 | 0.76 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.55 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.55 |
| ▸ | CDK2 | P24941 | 3/20 | 0.55 |
| ▸ | CCNK | O75909 | 2/20 | 0.55 |
| ▸ | CDK9 | P50750 | 2/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | CCND3 | P30281 | 1/20 | 0.51 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22462158 | 0.89 | ALK (0.71) | INSRALK | |
| SCHEMBL18159214 | 0.87 | ALK (0.75) | INSRALKLRRK2CCNA2CDK2 | |
| SCHEMBL20085704 | 0.86 | ALK (1.00) | INSRALK | |
| SCHEMBL18159219 | 0.80 | ALK (0.75) | INSRALKLRRK2CCNA2CDK2 | |
| SCHEMBL18159232 | 0.80 | INSR (0.77) | INSRALKLRRK2CCNA2CDK2 | |
| SCHEMBL25566394 | 0.80 | ALK (0.63) | INSRALK | |
| SCHEMBL25565571 | 0.80 | ALK (0.65) | INSRALK | |
| SCHEMBL18159224 | 0.79 | INSR (0.77) | INSRALKLRRK2CCNA2CDK2 | |
| SCHEMBL25574941 | 0.79 | ALK (0.69) | INSRALKLRRK2CDK2EGFR | |
| SCHEMBL23116181 | 0.79 | ALK (0.70) | INSRALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016167511-A2 | N2-(2-METHOXYPHENYL)PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR CANCER PREVENTION OR TREATMENT CONTAINING SAME AS ACTIVE INGREDIENT | 한국화학연구원 | 2016-10-20 | — | — | WO | disclosed |