Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 15/20 | 0.74 |
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | RET | P07949 | 2/20 | 0.50 |
| ▸ | CDK8 | P49336 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PLK4 | O00444 | 1/20 | 0.50 |
| ▸ | CIT | O14578 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | MUSK | O15146 | 1/20 | 0.50 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.50 |
| ▸ | MLNR | O43193 | 1/20 | 0.50 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.50 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.50 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.50 |
| ▸ | PDE6D | O43924 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | STK10 | O94804 | 1/20 | 0.50 |
| ▸ | CDK14 | O94921 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13529051 | 0.85 | RAF1 (1.00) | RAF1KDRRETCDK8MEN1 | |
| SCHEMBL13556607 | 0.84 | NPC1 (0.62) | RAF1MEN1MAPK13MAPK1MAPK12 | |
| SCHEMBL10324287 | 0.81 | RAF1 (0.75) | RAF1KDRRETCDK8MEN1 | |
| SCHEMBL1506293 | 0.80 | RAF1 (0.67) | RAF1KDRRETPLK4AURKA | |
| SCHEMBL15612734 | 0.80 | RAF1 (0.70) | RAF1KDRRETMEN1PLK4 | |
| SCHEMBL14009183 | 0.78 | RAF1 (0.56) | RAF1KDRRETCDK8MEN1 | |
| SCHEMBL257694 | 0.76 | MMP13 (0.71) | RAF1MEN1KMT2AAR | |
| SCHEMBL14550532 | 0.76 | RAF1 (0.55) | RAF1KDRRETCDK8MEN1 | |
| SCHEMBL10163566 | 0.75 | RAF1 (0.71) | RAF1MEN1BRAFKMT2AAR | |
| SCHEMBL258013 | 0.75 | RAF1 (0.63) | RAF1KDRMEN1BRAFKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9994515-B2 | Aryl naphthyl methanone oxime(s) and process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-06-12 | — | — | US | disclosed |
| US-20160304442-A1 | ARYL NAPHTHYL METHANONE OXIME(S) AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304442-A1 | ARYL NAPHTHYL METHANONE OXIME(S) AND PROCESS FOR PREPARATION THEREOF | MCL1, CYP11B1, CYP21A2 | RAF1 655/4885KDR 4266/4885RET 4633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.