Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 19/20 | 0.82 |
| ▸ | FLT3 | P36888 | 6/20 | 0.82 |
| ▸ | KIT | P10721 | 5/20 | 0.82 |
| ▸ | CSF1R | P07333 | 3/20 | 0.82 |
| ▸ | PLK4 | O00444 | 1/20 | 0.82 |
| ▸ | GAK | O14976 | 1/20 | 0.82 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.82 |
| ▸ | STK10 | O94804 | 1/20 | 0.82 |
| ▸ | EGFR | P00533 | 1/20 | 0.82 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.82 |
| ▸ | LCK | P06239 | 1/20 | 0.82 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.82 |
| ▸ | SRC | P12931 | 1/20 | 0.82 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.82 |
| ▸ | FLT1 | P17948 | 1/20 | 0.82 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.82 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.82 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.82 |
| ▸ | AXL | P30530 | 1/20 | 0.82 |
| ▸ | FLT4 | P35916 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tandutinib SCHEMBL927974 | 0.90 | PDGFRB (1.00) | PDGFRBFLT3KITCSF1RPLK4 | |
| Tandutinib SCHEMBL29393910 | 0.90 | PDGFRB (1.00) | PDGFRBFLT3KITCSF1RPLK4 | |
| Tandutinib SCHEMBL2478362 | 0.90 | PDGFRB (0.98) | PDGFRBFLT3KITCSF1RPLK4 | |
| SCHEMBL13330466 | 0.90 | PDGFRB (1.00) | PDGFRBFLT3KITCSF1RPLK4 | |
| Tandutinib SCHEMBL2496722 | 0.87 | PDGFRB (0.93) | PDGFRBFLT3KITCSF1RPLK4 | |
| SCHEMBL13330462 | 0.87 | PDGFRB (1.00) | PDGFRBFLT3KITCSF1RPLK4 | |
| SCHEMBL13524739 | 0.84 | PDGFRB (0.90) | PDGFRBFLT3KITCSF1RPLK4 | |
| SCHEMBL13114412 | 0.84 | PDGFRB (0.79) | PDGFRBFLT3KITCSF1RPLK4 | |
| SCHEMBL13529590 | 0.84 | PDGFRB (0.89) | PDGFRBFLT3KITCSF1RPLK4 | |
| SCHEMBL13330482 | 0.83 | PDGFRB (0.88) | PDGFRBFLT3KITCSF1RPLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9994515-B2 | Aryl naphthyl methanone oxime(s) and process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-06-12 | — | — | US | disclosed |
| US-20160304442-A1 | ARYL NAPHTHYL METHANONE OXIME(S) AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304442-A1 | ARYL NAPHTHYL METHANONE OXIME(S) AND PROCESS FOR PREPARATION THEREOF | MCL1, CYP11B1, CYP21A2 | PDGFRB 1574/4885FLT3 648/4885KIT 386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.