Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24319186 | 1.00 | KDM4E (0.50) | KDM4EGLAGAAMEN1KMT2A | |
| SCHEMBL24319503 | 1.00 | KDM4E (0.50) | KDM4EGLAGAAMEN1KMT2A | |
| SCHEMBL2800684 | 0.91 | KMT2A (0.48) | KDM4EGLAMEN1KMT2AALDH1A1 | |
| SCHEMBL11668191 | 0.91 | — | — | |
| SCHEMBL14078770 | 0.88 | KDM4E (0.47) | KDM4EGLAGAAMEN1KMT2A | |
| SCHEMBL24672708 | 0.85 | SLC18A3 (0.45) | KDM4EGLAMEN1KMT2AALDH1A1 | |
| SCHEMBL11131278 | 0.84 | KDM4E (0.58) | KDM4EGLAGAAMEN1KMT2A | |
| SCHEMBL5825167 | 0.83 | KDM4E (0.39) | KDM4EGLAGAAMEN1KMT2A | |
| SCHEMBL5907323 | 0.83 | KDM4E (0.50) | KDM4EGLAGAAMEN1KMT2A | |
| SCHEMBL24319428 | 0.83 | KDM4E (0.53) | KDM4EGLAGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9994515-B2 | Aryl naphthyl methanone oxime(s) and process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-06-12 | — | — | US | disclosed |
| US-20160304442-A1 | ARYL NAPHTHYL METHANONE OXIME(S) AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304442-A1 | ARYL NAPHTHYL METHANONE OXIME(S) AND PROCESS FOR PREPARATION THEREOF | MCL1, CYP11B1, CYP21A2 | KDM4E 364/4885GLA 3490/4885GAA 4292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.