Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14351532 | 1.00 | REN (0.62) | REN | |
| SCHEMBL1820519 | 1.00 | REN (0.62) | REN | |
| SCHEMBL12234422 | 1.00 | REN (0.62) | REN | |
| SCHEMBL1819522 | 1.00 | REN (0.62) | REN | |
| SCHEMBL1823236 | 1.00 | REN (0.62) | REN | |
| SCHEMBL1821821 | 1.00 | REN (0.62) | REN | |
| SCHEMBL1823232 | 1.00 | REN (0.62) | REN | |
| SCHEMBL1820521 | 1.00 | REN (0.62) | REN | |
| SCHEMBL12234371 | 0.95 | REN (0.61) | REN | |
| SCHEMBL12239118 | 0.95 | REN (0.57) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2499120-A1 | NOVEL 1,3-OXAZOLIDINE COMPOUNDS AND THEIR USE AS RENIN INHIBITORS | Novadex Pharmaceuticals AB (SE) | 2012-09-19 | — | — | EP | disclosed |
| WO-2011056126-A1 | NOVEL 1,3-OXAZOLIDINE COMPOUNDS AND THEIR USE AS RENIN INHIBITORS | NOVADEX PHARMACEUTICALS AB (SE) | 2011-05-12 | — | — | WO | disclosed |