Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 7/20 | 0.42 |
| ▸ | P2RX2 | Q9UBL9 | 7/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18166402 | 0.92 | P2RX3 (0.43) | P2RX3P2RX2HPGDSKCNK3 | |
| SCHEMBL18166428 | 0.92 | P2RX3 (0.44) | P2RX3P2RX2P2RX7HPGDS | |
| SCHEMBL18166349 | 0.92 | P2RX3 (0.48) | P2RX3P2RX2 | |
| SCHEMBL18166380 | 0.92 | P2RX3 (0.48) | P2RX3P2RX2 | |
| SCHEMBL18166442 | 0.90 | P2RX3 (0.55) | P2RX3P2RX2P2RX7HPGDSKCNK3 | |
| SCHEMBL18166304 | 0.89 | P2RX3 (0.51) | P2RX3P2RX2HPGDS | |
| SCHEMBL18166341 | 0.89 | P2RX3 (0.51) | P2RX3P2RX2HPGDS | |
| SCHEMBL10244289 | 0.88 | P2RX3 (0.56) | P2RX3P2RX2 | |
| SCHEMBL18166271 | 0.87 | P2RX3 (0.48) | P2RX3P2RX2 | |
| SCHEMBL18166268 | 0.86 | P2RX3 (0.49) | P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |