Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.32 |
| ▸ | VNN1 | O95497 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18166297 | 1.00 | P2RX3 (0.41) | P2RX3P2RX2PHGDHGPR139LMNA | |
| SCHEMBL18166411 | 1.00 | P2RX3 (0.41) | P2RX3P2RX2PHGDHGPR139LMNA | |
| SCHEMBL18166279 | 0.92 | P2RX3 (0.42) | P2RX3P2RX2PHGDHGPR139LMNA | |
| SCHEMBL10243787 | 0.87 | P2RX3 (0.55) | P2RX3P2RX2PHGDH | |
| SCHEMBL10244468 | 0.87 | P2RX3 (0.55) | P2RX3P2RX2PHGDH | |
| SCHEMBL18166273 | 0.87 | P2RX3 (0.57) | P2RX3P2RX2 | |
| SCHEMBL18036303 | 0.85 | P2RX3 (0.39) | P2RX3P2RX2LMNATP53HSP90AA1 | |
| SCHEMBL18036389 | 0.85 | P2RX3 (0.39) | P2RX3P2RX2LMNATP53HSP90AA1 | |
| SCHEMBL18036321 | 0.85 | P2RX3 (0.39) | P2RX3P2RX2LMNATP53HSP90AA1 | |
| SCHEMBL18166385 | 0.84 | P2RX3 (0.41) | P2RX3P2RX2PHGDHGPR139LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |