Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 5/20 | 0.56 |
| ▸ | P2RX2 | Q9UBL9 | 5/20 | 0.56 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18166276 | 0.93 | P2RX3 (0.61) | P2RX3P2RX2 | |
| SCHEMBL18166270 | 0.93 | P2RX3 (0.55) | P2RX3P2RX2KCNK3HPGDS | |
| SCHEMBL18166442 | 0.93 | P2RX3 (0.55) | P2RX3P2RX2KCNK3HPGDS | |
| SCHEMBL18166299 | 0.91 | P2RX3 (0.66) | P2RX3P2RX2 | |
| SCHEMBL18166388 | 0.88 | P2RX3 (0.55) | P2RX3P2RX2 | |
| SCHEMBL10244422 | 0.88 | P2RX3 (0.73) | P2RX3P2RX2 | |
| SCHEMBL18166412 | 0.87 | P2RX3 (0.50) | P2RX3P2RX2KCNK3 | |
| SCHEMBL18166415 | 0.86 | P2RX3 (0.56) | P2RX3P2RX2KCNK3HPGDS | |
| SCHEMBL18166355 | 0.86 | P2RX3 (0.61) | P2RX3P2RX2 | |
| SCHEMBL18166267 | 0.85 | P2RX3 (0.77) | P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |