Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.54 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18166407 | 0.88 | P2RX3 (0.41) | P2RX3P2RX2LMNAMAPTMEN1 | |
| SCHEMBL10244804 | 0.87 | P2RX3 (0.71) | P2RX3P2RX2 | |
| SCHEMBL18166363 | 0.84 | P2RX3 (0.57) | P2RX3P2RX2LMNAMAPTTRPV1 | |
| SCHEMBL18166400 | 0.84 | P2RX3 (0.61) | P2RX3P2RX2LMNAMAPTMAPK1 | |
| SCHEMBL18166461 | 0.84 | P2RX3 (0.58) | P2RX3P2RX2 | |
| SCHEMBL18166450 | 0.84 | P2RX3 (0.54) | P2RX3P2RX2LMNAMAPTNPC1 | |
| SCHEMBL18166326 | 0.84 | P2RX3 (0.77) | P2RX3P2RX2 | |
| SCHEMBL18166267 | 0.84 | P2RX3 (0.77) | P2RX3P2RX2 | |
| SCHEMBL18166334 | 0.84 | P2RX3 (0.77) | P2RX3P2RX2 | |
| SCHEMBL18166280 | 0.84 | P2RX3 (0.56) | P2RX3P2RX2LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |