Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 5/20 | 0.42 |
| ▸ | P2RX2 | Q9UBL9 | 5/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 7/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18166423 | 0.93 | P2RX3 (0.40) | P2RX3P2RX2ACKR3KCNK3PRCP | |
| SCHEMBL18166337 | 0.89 | P2RX3 (0.45) | P2RX3P2RX2ACKR3KCNK3 | |
| SCHEMBL10244905 | 0.88 | P2RX3 (0.55) | P2RX3P2RX2ACKR3 | |
| SCHEMBL18166402 | 0.88 | P2RX3 (0.43) | P2RX3P2RX2ACKR3KCNK3FAAH | |
| SCHEMBL18166415 | 0.87 | P2RX3 (0.56) | P2RX3P2RX2ACKR3KCNK3 | |
| SCHEMBL18166405 | 0.86 | P2RX3 (0.56) | P2RX3P2RX2 | |
| SCHEMBL18036369 | 0.84 | TP53 (0.37) | P2RX3P2RX2ACKR3PRCPTP53 | |
| SCHEMBL18036377 | 0.82 | TP53 (0.38) | ACKR3PRCPTP53FAAH | |
| SCHEMBL18166463 | 0.82 | P2RX3 (0.49) | P2RX3P2RX2 | |
| SCHEMBL18166358 | 0.81 | P2RX3 (0.44) | P2RX3P2RX2ACKR3KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |