SCHEMBL18167015

SCHEMBL18167015

OC1C[C@@H](O)[C@H](O)C(O)C1O

nearest known ligand 0.59

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
APP P05067 1/20 0.46
FUCA1 P04066 2/20 0.41
GBA1 P04062 2/20 0.41
GLA P06280 2/20 0.41
GAA P10253 1/20 0.41
THRB P10828 1/20 0.33
GLB1 P16278 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15484399 1.00 LMNA (0.46) LMNAAPPFUCA1GBA1GLA
SCHEMBL14771462 1.00 LMNA (0.46) LMNAAPPFUCA1GBA1GLA
SCHEMBL12858619 1.00 LMNA (0.46) LMNAAPPFUCA1GBA1GLA
SCHEMBL14542553 1.00 LMNA (0.46) LMNAAPPFUCA1GBA1GLA
SCHEMBL5151166 1.00 LMNA (0.46) LMNAAPPFUCA1GBA1GLA
SCHEMBL1681800 1.00 LMNA (0.46) LMNAAPPFUCA1GBA1GLA
SCHEMBL12679333 1.00 LMNA (0.46) LMNAAPPFUCA1GBA1GLA
SCHEMBL6079050 1.00 LMNA (0.46) LMNAAPPFUCA1GBA1GLA
SCHEMBL17925160 1.00 LMNA (0.46) LMNAAPPFUCA1GBA1GLA
SCHEMBL14534396 1.00 LMNA (0.46) LMNAAPPFUCA1GBA1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3085782-A1 2-DEOXY-SCYLLO-INOSOSE REDUCTASE Asahi Kasei Chemicals Corporation (JP) 2016-10-26 EP disclosed