Cephaeline

Cephaeline

SCHEMBL181711

CC[C@H]1CN2CCc3cc(OC)c(OC)cc3[C@@H]2C[C@@H]1C[C@H]1NCCc2cc(O)c(OC)cc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 7/20 1.00
EPAS1 Q99814 3/20 1.00
SMN1; SMN2 Q16637 5/20 0.96
LMNA P02545 4/20 0.96
CYP2D6 P10635 2/20 0.96
MEN1 O00255 6/20 0.89
KMT2A Q03164 6/20 0.89
SLC2A1 P11166 5/20 0.89
CYP3A4 P08684 3/20 0.89
MAPK1 P28482 3/20 0.89
NPC1 O15118 3/20 0.89
RAB9A P51151 3/20 0.89
MAPT P10636 2/20 0.89
STAT6 P42226 2/20 0.89
TP53 P04637 1/20 0.89
NFKB1 P19838 1/20 0.89
THPO P40225 1/20 0.89
HTT P42858 1/20 0.89
RBBP9 O75884 1/20 0.89
ABCB1 P08183 1/20 0.89

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cephaeline SCHEMBL13912580 1.00 HIF1A (1.00) HIF1AEPAS1SMN1; SMN2LMNACYP2D6
Cephaeline SCHEMBL29380707 1.00 HIF1A (1.00) HIF1AEPAS1SMN1; SMN2LMNACYP2D6
Cephaeline SCHEMBL2518794 0.99 HIF1A (0.98) HIF1AEPAS1SMN1; SMN2LMNACYP2D6
Emetine SCHEMBL11052542 0.99 HIF1A (0.98) HIF1AEPAS1SMN1; SMN2LMNACYP2D6
Cephaeline SCHEMBL31256787 0.99 HIF1A (0.98) HIF1AEPAS1SMN1; SMN2LMNACYP2D6
Cephaeline SCHEMBL19742946 0.99 HIF1A (0.98) HIF1AEPAS1SMN1; SMN2LMNACYP2D6
Cephaeline SCHEMBL2381570 0.98 HIF1A (1.00) HIF1AEPAS1SMN1; SMN2LMNACYP2D6
Cephaeline SCHEMBL20873862 0.97 HIF1A (0.93) HIF1AEPAS1SMN1; SMN2LMNACYP2D6
Emetine SCHEMBL24499457 0.94 HIF1A (1.00) HIF1AEPAS1SMN1; SMN2LMNACYP2D6
Emetine SCHEMBL14029342 0.94 HIF1A (1.00) HIF1AEPAS1SMN1; SMN2LMNACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 826 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026086871-A1 ANTI-AGEING COMPOUNDS, USES THEREFOR, METHOD FOR IDENTIFYING, AND COMPOSITIONS CONTAINING Centre for Translational Stem Cell Biology Limited (CN) 2026-04-30 WO claimed
EP-4677612-A1 METHODS FOR DETERMINING DRUG CANDIDATES mosaiques diagnostics & therapeutics AG (DE) 2026-01-14 EP claimed
CN-119233997-A Tetrahedral antibodies 生物分子控股有限责任公司 2024-12-31 CN claimed
EP-4463485-A2 TETRAHEDRAL ANTIBODIES Biomolecular Holdings LLC (US) 2024-11-20 EP claimed
WO-2024213057-A1 USE OF COMBINATION OF LSD1 INHIBITOR AND DRUG TO TREAT CANCER 中国科学院上海药物研究所 2024-10-17 WO claimed
WO-2024184437-A1 METHODS FOR DETERMINING DRUG CANDIDATES MOSAIQUES DIAGNOSTICS AND THERAPEUTICS AG (DE) 2024-09-12 WO claimed
EP-4428869-A1 METHODS FOR DETERMINING DRUG CANDIDATES mosaiques diagnostics & therapeutics AG (DE) 2024-09-11 EP claimed
WO-2024175719-A1 COMPOUNDS AND METHODS FOR TREATING AND/OR ALLEVIATING THE SIDE EFFECTS OF MYOCARDIAL INFARCTION SYDDANSK UNIVERSITET (DK) 2024-08-29 WO claimed
WO-2023219526-A1 MULTITARGET ANTIVIRAL DIETARY SUPPLEMENT PROKIN MILAN (RS) 2023-11-16 WO claimed
US-20230346820-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF SARS-COV-2 THE SCRIPPS RESEARCH INSTITUTE 2023-11-02 US claimed
CN-1679955-A Pharmaceutical composition capable of improving medication safety LOTUS PHARMACEUTICAL CO LTD (CN) 2005-10-12 CN claimed
US-20050220715-A1 Methods and compositions for improving drug safety LOTUS PHARMACEUTICAL CO., LTD. (TW) 2005-10-06 US claimed
WO-2005018616-A1 METHOD FOR DETERRING ABUSE OF OPIOIDS BY COMBINATION WITH NON-RELEASE FORMULATION OF EMETIC ENDO PHARMACEUTICALS, INC. (US) 2005-03-03 WO claimed
WO-2005004989-A2 FILM COMPRISING THERAPEUTIC AGENTS MAIBACH TODD (US) 2005-01-20 WO claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
US-4529583-A Composition and method of immobilizing emetics and method of treating human beings with emetics CLEAR LAKE DEVELOPMENT GROUP (US) 1985-07-16 US claimed
US-4459278-A Composition and method of immobilizing emetics and method of treating human beings with emetics CLEAR LAKE DEVELOPMENT GROUP (US) 1984-07-10 US claimed
US-4175119-A Composition and method to prevent accidental and intentional overdosage with psychoactive drugs PORTER GARRY L 1979-11-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230346820-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF SARS-COV-2 ACE2, SARS1, ACE HIF1A 2031/4885EPAS1 2738/4885SMN1; SMN2 2055/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.