Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 1.00 |
| ▸ | MEN1 | O00255 | 6/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 6/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 1.00 |
| ▸ | SLC2A1 | P11166 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 1.00 |
| ▸ | NPC1 | O15118 | 3/20 | 1.00 |
| ▸ | RAB9A | P51151 | 3/20 | 1.00 |
| ▸ | EPAS1 | Q99814 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | STAT6 | P42226 | 2/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 1/20 | 1.00 |
| ▸ | THPO | P40225 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | RBBP9 | O75884 | 1/20 | 1.00 |
| ▸ | ABCB1 | P08183 | 1/20 | 1.00 |
| ▸ | HTR1A | P08908 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Emetine SCHEMBL14135123 | 1.00 | HIF1A (1.00) | HIF1AMEN1KMT2ASMN1; SMN2SLC2A1 | |
| Emetine SCHEMBL29392786 | 1.00 | HIF1A (1.00) | HIF1AMEN1KMT2ASMN1; SMN2SLC2A1 | |
| Emetine SCHEMBL14261157 | 1.00 | HIF1A (1.00) | HIF1AMEN1KMT2ASMN1; SMN2SLC2A1 | |
| Emetine SCHEMBL29390500 | 1.00 | HIF1A (1.00) | HIF1AMEN1KMT2ASMN1; SMN2SLC2A1 | |
| Emetine SCHEMBL13226748 | 1.00 | HIF1A (1.00) | HIF1AMEN1KMT2ASMN1; SMN2SLC2A1 | |
| Emetine SCHEMBL14269958 | 1.00 | HIF1A (1.00) | HIF1AMEN1KMT2ASMN1; SMN2SLC2A1 | |
| Emetine SCHEMBL14029342 | 1.00 | HIF1A (1.00) | HIF1AMEN1KMT2ASMN1; SMN2SLC2A1 | |
| Emetine SCHEMBL56277 | 1.00 | HIF1A (1.00) | HIF1AMEN1KMT2ASMN1; SMN2SLC2A1 | |
| Emetine SCHEMBL13912579 | 1.00 | HIF1A (1.00) | HIF1AMEN1KMT2ASMN1; SMN2SLC2A1 | |
| Emetine SCHEMBL2382448 | 0.99 | MEN1 (1.00) | HIF1AMEN1KMT2ASMN1; SMN2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022120209-A1 | SOLID FORMS OF EMETINE | ACER THERAPEUTICS, INC. (US) | 2022-06-09 | — | — | WO | disclosed |