Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 6/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 5/20 | 0.53 |
| ▸ | SLC1A1 | P43005 | 5/20 | 0.53 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1814055 | 1.00 | SLC1A2 (0.53) | SLC1A2SLC1A3SLC1A1GABRR1SLC7A5 | |
| SCHEMBL3997600 | 0.89 | BLM (0.53) | SLC1A2SLC1A3SLC1A1GABRR1SLC7A5 | |
| SCHEMBL3993617 | 0.84 | CHRM1 (0.52) | SLC1A2SLC1A3SLC1A1GABRR1ADRA1A | |
| SCHEMBL3994575 | 0.84 | CHRM1 (0.52) | SLC1A2SLC1A3SLC1A1GABRR1ADRA1A | |
| SCHEMBL3993568 | 0.84 | CHRM1 (0.52) | SLC1A2SLC1A3SLC1A1GABRR1ADRA1A | |
| SCHEMBL5695081 | 0.83 | SLC1A3 (0.50) | SLC1A2SLC1A3SLC1A1GABRR1SLC7A5 | |
| SCHEMBL5378219 | 0.83 | SLC1A3 (0.61) | SLC1A2SLC1A3SLC1A1GABRR1SLC7A5 | |
| SCHEMBL977889 | 0.83 | SLC1A3 (0.61) | SLC1A2SLC1A3SLC1A1GABRR1SLC7A5 | |
| Hydrochloric Acid SCHEMBL15688771 | 0.81 | SLC1A3 (0.59) | SLC1A2SLC1A3SLC1A1GABRR1SLC7A5 | |
| SCHEMBL3997624 | 0.81 | SLC1A2 (0.53) | SLC1A2SLC1A3SLC1A1ADRA1AGRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110130454-A1 | PRODRUGS OF GAMMA-AMINO ACID, ALPHA-2-DELTA LIGANDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | XENOPORT, INC. (US) | 2011-06-02 | — | — | US | disclosed |
| US-20110124705-A1 | PRODRUGS OF ALPHA-2-DELTA LIGANDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | XENOPORT, INC. (US) | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130454-A1 | PRODRUGS OF GAMMA-AMINO ACID, ALPHA-2-DELTA LIGANDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | CHRND, CHRNE, OPRD1 | SLC1A2 124/4885SLC1A3 491/4885SLC1A1 334/4885 |
| US-20110124705-A1 | PRODRUGS OF ALPHA-2-DELTA LIGANDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | CHRND, CHRNE, CHRNG | SLC1A2 1873/4885SLC1A3 3365/4885SLC1A1 2893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.