Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26185312 | 0.98 | ALDH1A1 (0.40) | SMN1; SMN2KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL28656530 | 0.95 | GAA (0.40) | SMN1; SMN2KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL31224201 | 0.83 | TSHR (0.59) | SMN1; SMN2KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL11559149 | 0.77 | ALDH1A1 (0.43) | SMN1; SMN2KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL18991664 | 0.76 | ALDH1A1 (0.35) | SMN1; SMN2ALDH1A1TSHRGAAPOLB | |
| SCHEMBL26131514 | 0.76 | ALDH1A1 (0.42) | SMN1; SMN2KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL16759629 | 0.76 | ALDH1A1 (0.55) | SMN1; SMN2KMT2AMEN1ALDH1A1TSHR | |
| Cyclopropane SCHEMBL2479617 | 0.75 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1TSHRGAAKDM4E | |
| SCHEMBL3631443 | 0.75 | ALDH1A1 (0.44) | SMN1; SMN2KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL28109077 | 0.75 | TSHR (0.42) | SMN1; SMN2ALDH1A1TSHRGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4624466-A1 | DEGRADER FOR DECOMPOSING CMET PROTEIN, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Innocure Therapeutics, Inc. (KR) | 2025-10-01 | — | — | EP | disclosed |
| EP-4594324-A1 | AZOLE DERIVATIVES AS SHP2 INHIBITORS | IRBM S.P.A. (IT) | 2025-08-06 | — | — | EP | disclosed |
| US-20230100838-A1 | COVALENT RAS INHIBITORS AND USES THEREOF | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2023-03-30 | — | — | US | disclosed |
| CN-105153119-B | Pyridine pyrimidinamine compound or pyridine pyridyl amine compound and its application | 广州必贝特医药技术有限公司 | 2019-01-01 | — | — | CN | disclosed |
| WO-2011063293-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIHELMINTH AGENTS | ANACOR PHARMACEUTICALS, INC. (US) | 2011-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230100838-A1 | COVALENT RAS INHIBITORS AND USES THEREOF | KRAS, NRAS, HRAS | SMN1; SMN2 4090/4885KMT2A 2080/4885MEN1 1775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.