Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | LDHB | P07195 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27851794 | 1.00 | NUDT1 (0.47) | NUDT1MAP4K4MAPK14CCNT1CDK9 | |
| SCHEMBL780421 | 1.00 | NUDT1 (0.47) | NUDT1MAP4K4MAPK14CCNT1CDK9 | |
| SCHEMBL18171857 | 0.87 | CCNT1 (0.44) | MAPK14CCNT1CDK9EGFR | |
| SCHEMBL27868798 | 0.86 | PFKFB3 (0.41) | PDGFRBPDGFRAPLK1MEN1MAPT | |
| SCHEMBL27851800 | 0.86 | TNF (0.42) | MAPK14EGFRPLK1PFKFB3 | |
| SCHEMBL782196 | 0.86 | PFKFB3 (0.41) | PDGFRBPDGFRAPLK1MEN1MAPT | |
| SCHEMBL780985 | 0.86 | TNF (0.42) | MAPK14EGFRPLK1PFKFB3 | |
| SCHEMBL782012 | 0.84 | PFKFB3 (0.47) | PDGFRBPDGFRAPLK1PFKFB3 | |
| SCHEMBL13049097 | 0.84 | NUDT1 (0.47) | NUDT1MAP4K4MAPK14CCNT1CDK9 | |
| SCHEMBL780785 | 0.79 | KCNH2 (0.43) | CDK9EGFRMEN1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016170163-A1 | SUBSTITUTED QUINOXALINES AND BENZOTRIAZINE P70S6 KINASE INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2016-10-27 | — | — | WO | disclosed |