Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.55 |
| ▸ | PPARD | Q03181 | 1/20 | 0.55 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.55 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.55 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11024665 | 0.85 | LCK (0.50) | LCKPPARDZDHHC20ZDHHC2GPR84 | |
| SCHEMBL2350390 | 0.85 | LCK (0.50) | LCKPPARDZDHHC20ZDHHC2GPR84 | |
| SCHEMBL27513963 | 0.85 | LCK (0.50) | LCKPPARDZDHHC20ZDHHC2GPR84 | |
| SCHEMBL1702508 | 0.85 | LCK (0.50) | LCKPPARDZDHHC20ZDHHC2GPR84 | |
| SCHEMBL11661583 | 0.85 | LCK (0.50) | LCKPPARDZDHHC20ZDHHC2GPR84 | |
| SCHEMBL11659422 | 0.85 | LCK (0.50) | LCKPPARDZDHHC20ZDHHC2GPR84 | |
| SCHEMBL26624434 | 0.85 | LCK (0.50) | LCKPPARDZDHHC20ZDHHC2GPR84 | |
| SCHEMBL7747945 | 0.83 | GPR84 (0.50) | LCKPPARDZDHHC20ZDHHC2GPR84 | |
| SCHEMBL16059073 | 0.83 | LCK (0.48) | LCKPPARDZDHHC20ZDHHC2GPR84 | |
| SCHEMBL7636971 | 0.83 | GPR84 (0.50) | LCKPPARDZDHHC20ZDHHC2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016172436-A1 | POLYCATIONIC AMPHIPHILES AND POLYMERS THEREOF AS ANTIMICROBIAL AGENTS AND METHODS USING SAME | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2016-10-27 | — | — | WO | disclosed |