Lithium

Lithium

SCHEMBL18173784

CCCC1C=Cc2ccccc21.[Li]

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.49
SIGMAR1 Q99720 6/20 0.41
HTR2A P28223 2/20 0.39
KDM4E B2RXH2 2/20 0.39
LMNA P02545 1/20 0.39
TP53 P04637 1/20 0.39
CHRM2 P08172 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CHRM1 P11229 1/20 0.39
DRD2 P14416 1/20 0.39
ADRA2B P18089 1/20 0.39
ADRA2C P18825 1/20 0.39
NFKB1 P19838 1/20 0.39
CHRM3 P20309 1/20 0.39
SLC6A2 P23975 1/20 0.39
HTR2C P28335 1/20 0.39
ADRA1A P35348 1/20 0.39
HRH1 P35367 1/20 0.39
DRD3 P35462 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29646288 0.98 HTR6 (0.50) HTR6SIGMAR1HTR2AKDM4ELMNA
SCHEMBL22452025 0.98 HTR6 (0.50) HTR6SIGMAR1HTR2AKDM4ELMNA
SCHEMBL1539577 0.98 HTR6 (0.50) HTR6SIGMAR1HTR2AKDM4ELMNA
SCHEMBL1028711 0.87 HTR6 (0.47) HTR6SIGMAR1HTR2AKDM4ELMNA
SCHEMBL668105 0.86 HTR6 (0.56) HTR6SIGMAR1HTR2AKDM4ELMNA
SCHEMBL2641527 0.85 HTR6 (0.46) HTR6SIGMAR1HTR2AKDM4ELMNA
SCHEMBL29546963 0.85 HTR6 (0.46) HTR6SIGMAR1HTR2AKDM4ELMNA
Methylamine SCHEMBL28004018 0.84 HTR6 (0.56) HTR6SIGMAR1HTR2AKDM4ELMNA
SCHEMBL6674209 0.84 HTR6 (0.45) HTR6SIGMAR1HTR2AKDM4ELMNA
SCHEMBL31185871 0.84 HTR6 (0.45) HTR6SIGMAR1HTR2AKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3274380-B1 CATALYST COMPOSITION COMPRISING FLUORIDED SUPPORT AND PROCESSES FOR USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC (US) 2020-08-19 EP disclosed
CN-107636029-B Catalyst compositions comprising fluorinated supports and methods of use thereof 埃克森美孚化学专利公司 2020-05-22 CN disclosed
US-10640583-B2 Catalyst composition comprising fluorided support and processes for use thereof EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2020-05-05 US disclosed
US-20180171040-A1 Catalyst Composition Comprising Fluorided Support and Processes for Use Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2018-06-21 US disclosed
EP-3274380-A1 CATALYST COMPOSITION COMPRISING FLUORIDED SUPPORT AND PROCESSES FOR USE THEREOF ExxonMobil Chemical Patents Inc. (US) 2018-01-31 EP disclosed
WO-2016171807-A1 CATALYST COMPOSITION COMPRISING FLUORIDED SUPPORT AND PROCESSES FOR USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-10-27 WO disclosed