Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18173884 | 1.00 | POLB (0.50) | POLBMAPTSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL17165500 | 0.87 | POLB (0.54) | POLBMAPTSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL17165501 | 0.87 | POLB (0.54) | POLBMAPTSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL18173886 | 0.82 | PPARG (0.44) | POLBMAPTSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL18173887 | 0.82 | PPARG (0.44) | POLBMAPTSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL24155332 | 0.79 | POLB (0.52) | POLBMAPTSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL21129671 | 0.78 | CYP1A2 (0.62) | POLBMAPTSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL17165499 | 0.78 | POLB (0.64) | POLBMAPTSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL15984874 | 0.76 | POLB (0.46) | POLBMAPTSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL19481187 | 0.74 | ALDH1A1 (0.57) | POLBMAPTSMN1; SMN2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016171470-A1 | BROMODOMAIN-INHIBITING COMPOUNDS AND METHODS TO PREVENT OR TREAT A CANCER | KAINOS MEDICINE, INC. (KR) | 2016-10-27 | — | — | WO | disclosed |