Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CPA1 | P15085 | 2/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.31 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8373941 | 0.80 | RNPEP (0.44) | RNPEPSLC7A5ALDH1A1CPA1SLC1A3 | |
| SCHEMBL8373938 | 0.80 | RNPEP (0.44) | RNPEPSLC7A5ALDH1A1CPA1SLC1A3 | |
| SCHEMBL19858949 | 0.78 | RNPEP (0.43) | RNPEPSLC7A5ALDH1A1CPA1SLC1A3 | |
| SCHEMBL19858948 | 0.78 | RNPEP (0.43) | RNPEPSLC7A5ALDH1A1CPA1SLC1A3 | |
| SCHEMBL2454573 | 0.77 | KDM4E (0.38) | MAPT | |
| SCHEMBL23182436 | 0.77 | RNPEP (0.46) | RNPEPSLC7A5ALDH1A1CPA1SLC1A3 | |
| SCHEMBL27094307 | 0.77 | RNPEP (0.41) | RNPEPSLC7A5ALDH1A1CPA1SLC1A3 | |
| SCHEMBL11161410 | 0.77 | RNPEP (0.46) | RNPEPSLC7A5ALDH1A1CPA1SLC1A3 | |
| SCHEMBL27094306 | 0.77 | RNPEP (0.41) | RNPEPSLC7A5ALDH1A1CPA1SLC1A3 | |
| SCHEMBL244271 | 0.73 | RNPEP (0.52) | RNPEPSLC7A5ALDH1A1CPA1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286168-A1 | A SOLID FORM OF APREMILAST AND A PROCESS FOR PREPARING THE SAME | Zentiva K.S. (CZ) | 2018-02-28 | — | — | EP | disclosed |
| WO-2016169533-A1 | A SOLID FORM OF APREMILAST AND A PROCESS FOR PREPARING THE SAME | ZENTIVA, K.S. (CZ) | 2016-10-27 | — | — | WO | disclosed |