SCHEMBL2454573

SCHEMBL2454573

CC(=O)N(I)C(CS)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38
THRB P10828 1/20 0.38
ALOX15 P16050 1/20 0.38
NFKB1 P19838 1/20 0.38
PTGS2 P35354 1/20 0.38
THPO P40225 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PTGS1 P23219 1/20 0.34
SLC7A11 Q9UPY5 1/20 0.34
ENPEP Q07075 4/20 0.32
ACE P12821 1/20 0.31
FOLH1 Q04609 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1054858 0.77 KDM4E (0.40) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL6419496 0.77
SCHEMBL29540353 0.77
SCHEMBL9122150 0.77 KDM4E (0.40) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL1054855 0.77 KDM4E (0.40) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL18174176 0.77 RNPEP (0.40) MAPT
SCHEMBL30165075 0.77
SCHEMBL7648952 0.76 KDM4E (0.39) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL28489157 0.76 KDM4E (0.39) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL28479862 0.76 KDM4E (0.39) KDM4EMAPTTHRBALOX15NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3967300-B1 COMPOSITION FOR THE PREVENTION AND TREATMENT OF INFECTIONS AND/OR INFLAMMATIONS ANVEST GROUP S R L (IT) 2023-08-16 EP claimed
EP-3967300-A1 COMPOSITION FOR THE PREVENTION AND TREATMENT OF INFECTIONS AND/OR INFLAMMATIONS Laboratori Nutriphyt S.r.l. (IT) 2022-03-16 EP claimed
US-20230392145-A1 PROMOTING NUTRIENT ABSORPTION THROUGH THE COLON CORNELL UNIVERSITY 2023-12-07 US disclosed
EP-3967300-B1 COMPOSITION FOR THE PREVENTION AND TREATMENT OF INFECTIONS AND/OR INFLAMMATIONS ANVEST GROUP S R L (IT) 2023-08-16 EP disclosed
EP-3967300-A1 COMPOSITION FOR THE PREVENTION AND TREATMENT OF INFECTIONS AND/OR INFLAMMATIONS Laboratori Nutriphyt S.r.l. (IT) 2022-03-16 EP disclosed
EP-3967300-A1 COMPOSITION FOR THE PREVENTION AND TREATMENT OF INFECTIONS AND/OR INFLAMMATIONS Laboratori Nutriphyt S.r.l. (IT) 2022-03-16 EP disclosed
US-20220008411-A1 TOLL-LIKE RECEPTOR 7 OR 8 AGONIST-CHOLESTEROL COMPLEX AND METHOD OF PREPARING SAME Research & Business Foundation Sungkyunkwan University (KR) 2022-01-13 US disclosed
EP-3889251-A1 CULTURE MEDIA FOR MYCOPLASMA Fundació Centre de Regulació Genòmica (ES) 2021-10-06 EP disclosed
EP-3838260-A1 IGG:TGF RII FUSION PROTEIN COMPOSITION Ares Trading S.A. (CH) 2021-06-23 EP disclosed
EP-2363122-B1 Implant pellet comprising clonidine to treat pain locally MEDTRONIC INC (US) 2014-06-11 EP disclosed
EP-2248517-B1 Concentrated mast cell stabilizing pharmaceutical formulations PARI PHARMA GMBH (DE) 2014-03-26 EP disclosed
WO-2004006900-A2 SULPHYDRYL COMPOUNDS IN COMBINATION WITH SULPHONE OR SULPHNAMIDE CONPOUNDS FOR USE IN MICROBIAL INFLAMMATORY DISEASES IMMUNE NETWORK LTD. (CA) 2004-01-22 WO disclosed
US-20020179103-A1 Antioxidant enzyme compositions for use with cigarettes HERSH THEODORE (US) 2002-12-05 US disclosed
US-20020117180-A1 Glutathione, green tea, grape seed extract to neutralize tobacco free radicals HERSH THEODORE (US) 2002-08-29 US disclosed
US-6415798-B1 SMOKE FILTER THIONE INTERNATIONAL, INC. 2002-07-09 US disclosed
US-6228347-B1 REDUCED GLUTATHIONE AND SELENIUM FOR GUM DISEASE THIONE INTERNATIONAL, INC. 2001-05-08 US disclosed
US-6011067-A THE COMBINATION OF L-GLUTATHIONE AND SELENIUM THAT ACTS AS ITS SYNERGISTIC CO-PARTNER, BOTH INCORPORATED IN A SUITABLE TOPICAL CARRIER. THIONE INTERNATIONAL, INC. (US) 2000-01-04 US disclosed
EP-0792137-A4 ANTIFUNGAL TREATMENT OF NAILS JOHNSON & JOHNSON CONSUMER (US) 1999-12-29 EP disclosed
EP-0792137-A1 ANTIFUNGAL TREATMENT OF NAILS JOHNSON & JOHNSON CONSUMER PRODUCTS, INC. (US) 1997-09-03 EP disclosed
WO-1996019186-A1 ANTIFUNGAL TREATMENT OF NAILS JOHNSON & JOHNSON CONSUMER PRODUCTS, INC. (US) 1996-06-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220008411-A1 TOLL-LIKE RECEPTOR 7 OR 8 AGONIST-CHOLESTEROL COMPLEX AND METHOD OF PREPARING SAME TLR8, TLR7, TLR3 KDM4E 3637/4885MAPT 4510/4885THRB 343/4885
US-20230392145-A1 PROMOTING NUTRIENT ABSORPTION THROUGH THE COLON FABP2, SLC10A2, SLC19A1 KDM4E 4496/4885MAPT 4844/4885THRB 270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.