Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4588700 | 0.80 | GAA (0.67) | MGAMGAASIMGAM2LMNA | |
| SCHEMBL18174486 | 0.79 | MGAM (0.36) | MGAMGAASIMGAM2 | |
| SCHEMBL3415360 | 0.78 | MGAM (0.53) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL18174485 | 0.76 | GAA (0.42) | MGAMGAASIMGAM2LMNA | |
| SCHEMBL3927375 | 0.76 | — | — | |
| SCHEMBL31588662 | 0.75 | MGAM (0.50) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL18174487 | 0.75 | MGAM (0.35) | MGAMGAASIMGAM2 | |
| SCHEMBL13586840 | 0.74 | MGAM (0.50) | MGAMGAASIMGAM2LMNA | |
| SCHEMBL3093021 | 0.74 | MGAM (0.57) | MGAMGAASIMGAM2LMNA | |
| Butane SCHEMBL3949759 | 0.74 | MGAM (0.57) | MGAMGAASIMGAM2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9475758-B2 | Compounds, method for preparation thereof and use thereof for preparing polymers useful for increasing heat resistance of polymeric compositions | FAURECIA INTERIEUR INDUSTRIE (FR) | 2016-10-25 | — | — | US | disclosed |