Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5205018 | 0.84 | GAA (0.64) | GAAMGAMSIMGAM2MCL1 | |
| SCHEMBL18174487 | 0.81 | MGAM (0.35) | GAAMGAMSIMGAM2 | |
| SCHEMBL18174486 | 0.80 | MGAM (0.36) | GAAMGAMSIMGAM2 | |
| SCHEMBL14898408 | 0.80 | GAA (0.41) | GAAMGAMSIMGAM2MCL1 | |
| SCHEMBL12072447 | 0.78 | MGAM (0.48) | GAAMGAMSIMGAM2MCL1 | |
| SCHEMBL18174489 | 0.76 | MGAM (0.40) | GAAMGAMSIMGAM2MCL1 | |
| Butane SCHEMBL3949759 | 0.75 | MGAM (0.57) | GAAMGAMSIMGAM2FAAH | |
| SCHEMBL5909428 | 0.74 | MCL1 (0.55) | MCL1FAAHALDH1A1MMP1MMP2 | |
| SCHEMBL3415360 | 0.74 | MGAM (0.53) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL10092871 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9475758-B2 | Compounds, method for preparation thereof and use thereof for preparing polymers useful for increasing heat resistance of polymeric compositions | FAURECIA INTERIEUR INDUSTRIE (FR) | 2016-10-25 | — | — | US | disclosed |