SCHEMBL18174559

SCHEMBL18174559

Cc1cc(-c2c3ccccc3c(-c3ccc(-c4cccnc4)c(C)c3)c3ccccc23)ccc1-c1cccnc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.54
CYP11B1 P15538 6/20 0.51
PDE3B Q13370 1/20 0.50
PDE3A Q14432 1/20 0.50
MKNK1 Q9BUB5 1/20 0.48
MKNK2 Q9HBH9 1/20 0.48
CYP2A6 P11509 3/20 0.47
CYP3A4 P08684 3/20 0.47
CYP2E1 P05181 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2B6 P20813 1/20 0.47
CYP2C19 P33261 1/20 0.47
CYP11B2 P19099 6/20 0.46
NPC1 O15118 1/20 0.44
TP53 P04637 1/20 0.44
MAPT P10636 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
DYRK1A Q13627 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174681 0.92 SLC2A1 (0.51) SLC2A1CYP11B1PDE3BPDE3AMKNK1
SCHEMBL15160968 0.92 SLC2A1 (0.51) SLC2A1CYP11B1PDE3BPDE3AMKNK1
SCHEMBL15160913 0.91 SLC2A1 (0.50) SLC2A1CYP11B1PDE3BPDE3AMKNK1
SCHEMBL18174694 0.89 SLC2A1 (0.49) SLC2A1CYP11B1PDE3BPDE3AMKNK1
SCHEMBL18174611 0.89 SLC2A1 (0.49) SLC2A1CYP11B1PDE3BPDE3AMKNK1
SCHEMBL15160973 0.89 SLC2A1 (0.46) SLC2A1CYP11B1PDE3BPDE3AMKNK1
SCHEMBL15160907 0.89 SLC2A1 (0.49) SLC2A1CYP11B1PDE3BPDE3AMKNK1
SCHEMBL15161029 0.88 SLC2A1 (0.48) SLC2A1CYP11B1PDE3BPDE3AMKNK1
SCHEMBL18174556 0.88 SLC2A1 (0.54) SLC2A1CYP11B1PDE3BPDE3AMKNK1
SCHEMBL18174601 0.87 CYP11B1 (0.56) SLC2A1CYP11B1PDE3BPDE3AMKNK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed