SCHEMBL18174556

SCHEMBL18174556

Cc1cc(-c2cccnc2)ccc1-c1c2ccccc2c(-c2ccc(-c3cccnc3)cc2C)c2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.54
MKNK1 Q9BUB5 2/20 0.51
MKNK2 Q9HBH9 2/20 0.51
CYP11B1 P15538 7/20 0.50
CYP11B2 P19099 6/20 0.50
CYP17A1 P05093 2/20 0.50
CYP19A1 P11511 2/20 0.50
CHEK1 O14757 1/20 0.48
AURKA O14965 1/20 0.48
DAPK3 O43293 1/20 0.48
JAK2 O60674 1/20 0.48
PRKD3 O94806 1/20 0.48
MAP4K4 O95819 1/20 0.48
PAK4 O96013 1/20 0.48
ABL1 P00519 1/20 0.48
LCK P06239 1/20 0.48
FYN P06241 1/20 0.48
CSF1R P07333 1/20 0.48
RET P07949 1/20 0.48
IGF1R P08069 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174573 0.93 SLC2A1 (0.49) SLC2A1MKNK1MKNK2CYP11B1CYP11B2
SCHEMBL18174637 0.92 SLC2A1 (0.48) SLC2A1MKNK1MKNK2CYP11B1CYP11B2
SCHEMBL18174617 0.91 SLC2A1 (0.47) SLC2A1MKNK1MKNK2CYP11B1CYP11B2
SCHEMBL18174609 0.91 SLC2A1 (0.47) SLC2A1MKNK1MKNK2CYP11B1CYP11B2
SCHEMBL18174679 0.89 SLC2A1 (0.46) SLC2A1MKNK1MKNK2CYP11B1CYP11B2
SCHEMBL18174682 0.89 SLC2A1 (0.52) SLC2A1MKNK1MKNK2CYP11B1CYP11B2
SCHEMBL18174656 0.89 SLC2A1 (0.49) SLC2A1MKNK1MKNK2CYP11B1CYP11B2
SCHEMBL18174593 0.88 CYP11B2 (0.61) SLC2A1MKNK1MKNK2CYP11B1CYP11B2
SCHEMBL18174707 0.88 SLC2A1 (0.46) SLC2A1MKNK1MKNK2CYP11B1CYP11B2
SCHEMBL18174569 0.88 CYP11B1 (0.50) SLC2A1MKNK1MKNK2CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed