SCHEMBL18174565

SCHEMBL18174565

Cc1ncccc1-c1cccc(-c2c3ccccc3c(-c3cccc(-c4cccnc4C)c3)c3ccccc23)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.45
MKNK1 Q9BUB5 1/20 0.43
MKNK2 Q9HBH9 1/20 0.43
PRMT5 O14744 1/20 0.41
WDR77 Q9BQA1 1/20 0.41
MAP4K4 O95819 2/20 0.40
CDC7 O00311 2/20 0.40
ROCK2 O75116 1/20 0.40
PIM1 P11309 1/20 0.40
PRKACA P17612 1/20 0.40
CDK2 P24941 1/20 0.40
GSK3B P49841 1/20 0.40
HIPK2 Q9H2X6 1/20 0.40
CLK4 Q9HAZ1 1/20 0.40
IRAK4 Q9NWZ3 1/20 0.40
TDO2 P48775 1/20 0.39
BRD4 O60885 3/20 0.38
CYP2A6 P11509 1/20 0.38
CCR1 P32246 1/20 0.38
CCR8 P51685 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9613009 0.91 DHODH (0.48) DHODHMKNK1MKNK2PRMT5WDR77
SCHEMBL15160994 0.90 DHODH (0.44) DHODHMKNK1MKNK2PRMT5WDR77
SCHEMBL9613001 0.88 COMT (0.46) DHODHMKNK1MKNK2PRMT5WDR77
SCHEMBL18174744 0.88 DHODH (0.40) DHODHMKNK1MKNK2PRMT5WDR77
SCHEMBL18174733 0.87 LRRK2 (0.41) DHODHMKNK1MKNK2MAP4K4CDC7
SCHEMBL10032712 0.86 DHODH (0.49) DHODHMKNK1MKNK2PRMT5WDR77
SCHEMBL10300940 0.86 DHODH (0.48) DHODHMKNK1MKNK2PRMT5WDR77
SCHEMBL10032694 0.85 DHODH (0.48) DHODHMKNK1MKNK2PRMT5WDR77
SCHEMBL15161058 0.85 DHODH (0.43) DHODHMKNK1MKNK2MAP4K4CDC7
SCHEMBL15161063 0.85 PIK3CA (0.43) DHODHMKNK1MKNK2MAP4K4PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed