SCHEMBL18174744

SCHEMBL18174744

Cc1ccc(-c2ccc(-c3c4ccccc4c(-c4cccc(-c5cccnc5C)c4)c4ccccc34)cc2)cn1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.40
PDK2 Q15119 1/20 0.38
MKNK1 Q9BUB5 1/20 0.38
MKNK2 Q9HBH9 1/20 0.38
ABL1 P00519 1/20 0.38
PRMT5 O14744 1/20 0.37
WDR77 Q9BQA1 1/20 0.37
METAP2 P50579 1/20 0.36
CDC7 O00311 1/20 0.36
ROCK2 O75116 1/20 0.36
MAP4K4 O95819 1/20 0.36
PIM1 P11309 1/20 0.36
PRKACA P17612 1/20 0.36
CDK2 P24941 1/20 0.36
GSK3B P49841 1/20 0.36
HIPK2 Q9H2X6 1/20 0.36
CLK4 Q9HAZ1 1/20 0.36
IRAK4 Q9NWZ3 1/20 0.36
PTGS2 P35354 3/20 0.35
TDO2 P48775 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15161055 0.95 DHODH (0.43) DHODHPDK2MKNK1MKNK2ABL1
SCHEMBL18174691 0.91 MKNK1 (0.46) DHODHPDK2MKNK1MKNK2ABL1
SCHEMBL18174565 0.88 DHODH (0.45) DHODHMKNK1MKNK2ABL1PRMT5
SCHEMBL16189031 0.86 PSD (0.39) PDK2ABL1PRMT5WDR77MAP4K4
SCHEMBL18174733 0.86 LRRK2 (0.41) DHODHPDK2MKNK1MKNK2CDC7
SCHEMBL17532879 0.85 ATM (0.39) PDK2ABL1PRMT5WDR77GSK3B
SCHEMBL15161063 0.85 PIK3CA (0.43) DHODHMKNK1MKNK2ABL1MAP4K4
SCHEMBL15160994 0.84 DHODH (0.44) DHODHMKNK1MKNK2ABL1PRMT5
SCHEMBL18174739 0.84 APLNR (0.39) DHODHMKNK1MKNK2ABL1PRMT5
SCHEMBL15161051 0.84 ABL1 (0.32) DHODHPDK2ABL1PRMT5WDR77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed