SCHEMBL18174582

SCHEMBL18174582

Cc1ccc(-c2cccnc2)cc1-c1c2ccccc2c(-c2cc(-c3cccnc3)ccc2C)c2cc(-c3ccccc3)ccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RET P07949 2/20 0.46
KDR P35968 2/20 0.46
CHEK1 O14757 2/20 0.46
CLK4 Q9HAZ1 2/20 0.46
AURKA O14965 1/20 0.46
DAPK3 O43293 1/20 0.46
JAK2 O60674 1/20 0.46
PRKD3 O94806 1/20 0.46
MAP4K4 O95819 1/20 0.46
PAK4 O96013 1/20 0.46
ABL1 P00519 1/20 0.46
LCK P06239 1/20 0.46
FYN P06241 1/20 0.46
CSF1R P07333 1/20 0.46
IGF1R P08069 1/20 0.46
MET P08581 1/20 0.46
PDGFRB P09619 1/20 0.46
PIM1 P11309 1/20 0.46
FGFR1 P11362 1/20 0.46
PDGFRA P16234 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174569 0.93 CYP11B1 (0.50) RETKDRCHEK1CLK4AURKA
SCHEMBL18174573 0.89 SLC2A1 (0.49) RETKDRCHEK1CLK4AURKA
SCHEMBL18174609 0.87 SLC2A1 (0.47) RETKDRCHEK1CLK4AURKA
SCHEMBL18174617 0.87 SLC2A1 (0.47) RETKDRCHEK1CLK4AURKA
SCHEMBL10030052 0.84 CYP11B1 (0.53) RETKDRCHEK1CLK4AURKA
SCHEMBL10030022 0.84 CYP11B1 (0.53) RETKDRCHEK1CLK4AURKA
SCHEMBL15977643 0.84 CYP11B1 (0.53) RETKDRCHEK1CLK4AURKA
SCHEMBL15977675 0.84 CYP11B1 (0.53) RETKDRCHEK1CLK4AURKA
SCHEMBL21742831 0.84 CYP11B1 (0.53) RETKDRCHEK1CLK4AURKA
SCHEMBL18422307 0.83 CYP11B1 (0.50) RETKDRCHEK1CLK4AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed