Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 6/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | PAK4 | O96013 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
| ▸ | RET | P07949 | 1/20 | 0.48 |
| ▸ | IGF1R | P08069 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18174582 | 0.93 | RET (0.46) | CYP11B1CYP11B2CYP17A1CYP19A1MKNK1 | |
| SCHEMBL18174556 | 0.88 | SLC2A1 (0.54) | CYP11B1CYP11B2CYP17A1CYP19A1MKNK1 | |
| SCHEMBL21742636 | 0.85 | CYP11B1 (0.54) | CYP11B1CYP11B2CYP17A1CYP19A1MKNK1 | |
| SCHEMBL21742831 | 0.84 | CYP11B1 (0.53) | CYP11B1CYP11B2CYP17A1CYP19A1MKNK1 | |
| SCHEMBL16593136 | 0.84 | CYP11B1 (0.53) | CYP11B1CYP11B2CYP17A1CYP19A1MKNK1 | |
| SCHEMBL10032920 | 0.82 | CYP11B2 (0.53) | CYP11B1CYP11B2CYP17A1CYP19A1PIM1 | |
| SCHEMBL10032872 | 0.82 | CYP11B2 (0.59) | CYP11B1CYP11B2CYP17A1CYP19A1CYP3A4 | |
| SCHEMBL18174573 | 0.81 | SLC2A1 (0.49) | CYP11B1CYP11B2CYP17A1CYP19A1MKNK1 | |
| SCHEMBL18174656 | 0.81 | SLC2A1 (0.49) | CYP11B1CYP11B2CYP17A1CYP19A1MKNK1 | |
| SCHEMBL15161108 | 0.81 | CYP11B1 (0.37) | CYP11B1CYP11B2CYP17A1CYP19A1MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9478750-B2 | Anthracene derivative and organic electroluminescent element using the same | JNC CORPORATION (JP) | 2016-10-25 | — | — | US | disclosed |
| US-9478750-B2 | Anthracene derivative and organic electroluminescent element using the same | JNC CORPORATION (JP) | 2016-10-25 | — | — | US | disclosed |