SCHEMBL18174586

SCHEMBL18174586

Cc1cccnc1-c1cccc(-c2c3ccccc3c(-c3cccc(-c4ncccc4C)c3)c3cc(-c4ccccc4)ccc23)c1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.44
TRPV1 Q8NER1 3/20 0.38
DHODH Q02127 1/20 0.38
EPHX2 P34913 1/20 0.37
ABL1 P00519 1/20 0.37
CNR2 P34972 1/20 0.36
GRIA2 P42262 1/20 0.36
IL1B P01584 1/20 0.35
CETP P11597 1/20 0.35
TNKS2 Q9H2K2 1/20 0.35
PSMB5 P28074 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
NR1H2 P55055 1/20 0.34
MKNK1 Q9BUB5 1/20 0.34
TTK P33981 1/20 0.34
HAO2 Q9NYQ3 1/20 0.34
PDK1 Q15118 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174610 0.95 CYP2A6 (0.44) CYP2A6TRPV1DHODHEPHX2CNR2
SCHEMBL18174641 0.92 CYP2A6 (0.44) CYP2A6TRPV1DHODHEPHX2CNR2
SCHEMBL15160986 0.92 CYP2A6 (0.46) CYP2A6TRPV1DHODHEPHX2CNR2
SCHEMBL15977631 0.92 CYP2A6 (0.46) CYP2A6TRPV1DHODHEPHX2CNR2
SCHEMBL10300898 0.92 CYP2A6 (0.49) CYP2A6TRPV1DHODHEPHX2ABL1
SCHEMBL18174566 0.90 CYP2A6 (0.53) CYP2A6TRPV1EPHX2ABL1CNR2
SCHEMBL10032690 0.88 ABL1 (0.46) CYP2A6TRPV1DHODHABL1CNR2
SCHEMBL10032927 0.87 ABL1 (0.42) CYP2A6TRPV1DHODHABL1CNR2
SCHEMBL15161044 0.86 LRRK2 (0.43) CYP2A6TRPV1
SCHEMBL13015542 0.85 CYP2A6 (0.58) CYP2A6TRPV1ABL1CNR2GRIA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed