SCHEMBL18174641

SCHEMBL18174641

Cc1cccnc1-c1ccc(-c2c3ccccc3c(-c3ccc(-c4ncccc4C)cc3)c3cc(-c4cc(-c5ccccc5)cc(-c5ccccc5)c4)ccc23)cc1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.44
DHODH Q02127 1/20 0.40
PDK1 Q15118 2/20 0.38
TRPV1 Q8NER1 5/20 0.37
MKNK1 Q9BUB5 1/20 0.37
CNR2 P34972 1/20 0.36
BCHE P06276 1/20 0.36
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
TOP1 P11387 1/20 0.35
EPHX2 P34913 1/20 0.35
TNKS2 Q9H2K2 1/20 0.35
HTR2B P41595 1/20 0.35
HTR5A P47898 1/20 0.35
TDO2 P48775 1/20 0.35
PSMB5 P28074 1/20 0.35
NQO2 P16083 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174610 0.97 CYP2A6 (0.44) CYP2A6DHODHPDK1TRPV1MKNK1
SCHEMBL15160986 0.97 CYP2A6 (0.46) CYP2A6DHODHPDK1TRPV1MKNK1
SCHEMBL15977631 0.97 CYP2A6 (0.46) CYP2A6DHODHPDK1TRPV1MKNK1
SCHEMBL18174586 0.92 CYP2A6 (0.44) CYP2A6DHODHPDK1TRPV1MKNK1
SCHEMBL10300898 0.92 CYP2A6 (0.49) CYP2A6DHODHPDK1TRPV1CNR2
SCHEMBL10032686 0.86 CYP2A6 (0.44) CYP2A6DHODHPDK1TRPV1CNR2
SCHEMBL18174567 0.85 CYP2A6 (0.53) CYP2A6DHODHPDK1TRPV1CNR2
SCHEMBL18174589 0.85 ABL1 (0.43) CYP2A6PDK1TRPV1CNR2HTR2B
SCHEMBL15977639 0.84 ABL1 (0.42) CYP2A6DHODHTRPV1CNR2HTR2B
SCHEMBL18431630 0.83 HTR2B (0.38) CYP2A6DHODHPDK1PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed