SCHEMBL18174664

SCHEMBL18174664

Cc1cc(-c2ccncc2)ccc1-c1c2ccccc2c(-c2ccc(-c3ccncc3)cc2C)c2cc(-c3cccc(-c4ccccc4)c3)ccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CA P42336 1/20 0.46
IMPDH2 P12268 1/20 0.45
MKNK1 Q9BUB5 1/20 0.43
LRRK2 Q5S007 4/20 0.43
NOTUM Q6P988 1/20 0.42
KIF11 P52732 1/20 0.39
CHEK1 O14757 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
RECQL P46063 1/20 0.38
KMT2A Q03164 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38
MAPK14 Q16539 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174574 0.97 PIK3CA (0.48) PIK3CAIMPDH2MKNK1LRRK2NOTUM
SCHEMBL18174604 0.92 PIK3CA (0.47) PIK3CAIMPDH2MKNK1LRRK2NOTUM
SCHEMBL18174557 0.90 MAPK14 (0.43) PIK3CAIMPDH2MKNK1LRRK2NOTUM
SCHEMBL18174603 0.89 PIK3CA (0.47) PIK3CAIMPDH2MKNK1LRRK2NOTUM
SCHEMBL15160985 0.89 PIK3CA (0.49) PIK3CAIMPDH2MKNK1LRRK2NOTUM
SCHEMBL18174609 0.88 SLC2A1 (0.47) PIK3CAMKNK1LRRK2KIF11CHEK1
SCHEMBL18174634 0.87 CA12 (0.48) PIK3CALRRK2KDM4EALDH1A1LMNA
SCHEMBL18174596 0.86 MAPK9 (0.43) PIK3CAIMPDH2CHEK1MAPTNPSR1
SCHEMBL18174617 0.85 SLC2A1 (0.47) PIK3CAMKNK1LRRK2KIF11CHEK1
SCHEMBL18174573 0.85 SLC2A1 (0.49) PIK3CAMKNK1LRRK2KIF11CHEK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed