SCHEMBL18174596

SCHEMBL18174596

Cc1cc(-c2ccncc2)ccc1-c1c2ccccc2c(-c2ccc(-c3ccncc3)cc2C)c2cc(-c3ccc4ccccc4c3)ccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK9 P45984 5/20 0.43
MAPK10 P53779 5/20 0.43
MAPK8 P45983 3/20 0.43
MAPK14 Q16539 6/20 0.41
CSNK1D P48730 5/20 0.41
MAPK11 Q15759 5/20 0.41
CHEK1 O14757 1/20 0.40
CYP17A1 P05093 1/20 0.40
CYP19A1 P11511 1/20 0.40
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
CYP2C9 P11712 1/20 0.38
PIK3CA P42336 1/20 0.38
HSD17B1 P14061 1/20 0.38
HSD17B2 P37059 1/20 0.38
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10032215 0.93 MAPK9 (0.43) MAPK9MAPK10MAPK8MAPK14CSNK1D
SCHEMBL18174585 0.91 MAPK9 (0.44) MAPK9MAPK10MAPK8MAPK14CSNK1D
SCHEMBL18174574 0.89 PIK3CA (0.48) MAPK14CHEK1CYP17A1PIK3CAMAPT
SCHEMBL18174557 0.87 MAPK14 (0.43) MAPK14CA12CA1CA2CA9
SCHEMBL18174634 0.87 CA12 (0.48) MAPK14CSNK1DMAPK11CA12CA1
SCHEMBL18174664 0.86 PIK3CA (0.46) MAPK14MAPK11CHEK1CYP17A1CA12
SCHEMBL18174593 0.86 CYP11B2 (0.61) MAPK9MAPK8CHEK1CYP17A1CYP19A1
SCHEMBL10030056 0.84 MAPK9 (0.50) MAPK9MAPK10MAPK8MAPK14CSNK1D
SCHEMBL15077951 0.84 MAPK9 (0.50) MAPK9MAPK10MAPK8MAPK14CSNK1D
SCHEMBL15977682 0.84 MAPK9 (0.50) MAPK9MAPK10MAPK8MAPK14CSNK1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed