SCHEMBL18174737

SCHEMBL18174737

Cc1ccncc1-c1ccc(-c2c3ccccc3c(-c3cccc(-c4cccnc4C)c3)c3ccccc23)cc1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 7/20 0.46
CYP1A2 P05177 6/20 0.46
DHODH Q02127 2/20 0.42
ABL1 P00519 3/20 0.41
WNT1 P04628 1/20 0.41
PTGES2 Q9H7Z7 1/20 0.40
CYP11B1 P15538 3/20 0.40
CYP11B2 P19099 3/20 0.40
PTGS2 P35354 1/20 0.39
MKNK1 Q9BUB5 1/20 0.39
MKNK2 Q9HBH9 1/20 0.39
GRIA2 P42262 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15161050 1.00 CYP17A1 (0.46) CYP17A1CYP1A2DHODHABL1WNT1
SCHEMBL18174688 0.93 CYP17A1 (0.46) CYP17A1CYP1A2DHODHABL1WNT1
SCHEMBL18174755 0.91 DHODH (0.41) CYP17A1CYP1A2DHODHPTGS2MKNK1
SCHEMBL18174724 0.90 CYP17A1 (0.51) CYP17A1CYP1A2DHODHABL1PTGES2
SCHEMBL15161063 0.86 PIK3CA (0.43) CYP17A1CYP1A2DHODHABL1CYP11B1
SCHEMBL15161107 0.86 CYP17A1 (0.51) CYP17A1CYP1A2DHODHABL1PTGES2
SCHEMBL15161094 0.86 CYP2A6 (0.49) CYP17A1CYP1A2DHODHABL1WNT1
SCHEMBL18174797 0.85 CYP17A1 (0.45) CYP17A1CYP1A2DHODHPTGS2MKNK1
SCHEMBL15161087 0.85 CYP17A1 (0.47) CYP17A1CYP1A2DHODHABL1CYP11B1
SCHEMBL15161084 0.85 CYP17A1 (0.47) CYP17A1CYP1A2DHODHABL1PTGES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed