SCHEMBL18174797

SCHEMBL18174797

Cc1ccncc1-c1ccc(-c2c3ccccc3c(-c3ccc(-c4cccnc4C)cc3)c3ccccc23)c2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 16/20 0.45
CYP1A2 P05177 15/20 0.45
DHODH Q02127 2/20 0.42
MKNK1 Q9BUB5 1/20 0.40
MKNK2 Q9HBH9 1/20 0.40
PTGS2 P35354 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174688 0.92 CYP17A1 (0.46) CYP17A1CYP1A2DHODHMKNK1MKNK2
SCHEMBL18174794 0.90 DHODH (0.42) CYP17A1CYP1A2DHODHMKNK1MKNK2
SCHEMBL18174788 0.88 DHODH (0.50) CYP17A1CYP1A2DHODHPTGS2
SCHEMBL18174795 0.85 DHODH (0.46) DHODHMKNK1MKNK2
SCHEMBL15161050 0.85 CYP17A1 (0.46) CYP17A1CYP1A2DHODHMKNK1MKNK2
SCHEMBL18174737 0.85 CYP17A1 (0.46) CYP17A1CYP1A2DHODHMKNK1MKNK2
SCHEMBL18174774 0.85 PTGS2 (0.47) DHODHMKNK1MKNK2PTGS2
SCHEMBL18174635 0.84 MKNK1 (0.43) CYP17A1CYP1A2DHODHMKNK1MKNK2
SCHEMBL18174759 0.84 CYP17A1 (0.46) CYP17A1CYP1A2DHODHPTGS2
SCHEMBL9612969 0.84 DHODH (0.47) CYP1A2DHODHMKNK1MKNK2PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed