SCHEMBL18174746

SCHEMBL18174746

Cc1ccc(-c2cccc(-c3c4ccccc4c(-c4ccc(-c5cnccc5C)cc4)c4ccccc34)c2)nc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.47
CYP2A6 P11509 1/20 0.47
DHODH Q02127 1/20 0.44
CYP17A1 P05093 7/20 0.43
CYP1A2 P05177 5/20 0.43
CYP11B1 P15538 3/20 0.39
CYP11B2 P19099 3/20 0.39
PIM1 P11309 1/20 0.38
ABL1 P00519 3/20 0.38
WNT1 P04628 1/20 0.36
TGFBR1 P36897 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
RECQL P46063 1/20 0.36
KMT2A Q03164 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
PTGES2 Q9H7Z7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174659 0.92 CYP3A4 (0.49) CYP3A4CYP2A6DHODHCYP17A1CYP1A2
SCHEMBL18174752 0.91 CYP3A4 (0.47) CYP3A4CYP2A6DHODHCYP17A1CYP1A2
SCHEMBL18174719 0.88 DHODH (0.46) CYP2A6DHODHCYP17A1CYP1A2CYP11B1
SCHEMBL18174724 0.86 CYP17A1 (0.51) DHODHCYP17A1CYP1A2CYP11B1CYP11B2
SCHEMBL18174727 0.86 CYP2A6 (0.49) CYP2A6DHODHCYP17A1CYP1A2CYP11B1
SCHEMBL15161090 0.84 CYP2A6 (0.61) CYP3A4CYP2A6DHODHCYP17A1CYP11B1
SCHEMBL18174562 0.83 CYP3A4 (0.51) CYP3A4CYP2A6CYP11B1CYP11B2PIM1
SCHEMBL15160983 0.83 CYP17A1 (0.51) DHODHCYP17A1CYP1A2CYP11B1CYP11B2
SCHEMBL15161095 0.82 CYP2A6 (0.48) CYP2A6DHODHCYP17A1CYP1A2CYP11B1
SCHEMBL15161107 0.82 CYP17A1 (0.51) DHODHCYP17A1CYP1A2CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed