SCHEMBL18174752

SCHEMBL18174752

Cc1ccc(-c2cccc(-c3c4ccccc4c(-c4ccc(-c5ccncc5C)cc4)c4ccccc34)c2)nc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.47
CYP2A6 P11509 1/20 0.47
PIM1 P11309 2/20 0.38
CYP11B1 P15538 1/20 0.37
CYP11B2 P19099 1/20 0.37
GRM4 Q14833 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
RECQL P46063 1/20 0.36
KMT2A Q03164 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
CYP17A1 P05093 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP19A1 P11511 1/20 0.35
DHODH Q02127 1/20 0.35
S1PR1 P21453 2/20 0.35
S1PR3 Q99500 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174684 0.92 CYP3A4 (0.49) CYP3A4CYP2A6PIM1CYP11B1CYP11B2
SCHEMBL18174746 0.91 CYP3A4 (0.47) CYP3A4CYP2A6PIM1CYP11B1CYP11B2
SCHEMBL18174729 0.88 CYP2A6 (0.42) CYP2A6GRM4CYP17A1CYP1A2CYP19A1
SCHEMBL18174750 0.86 GRM4 (0.43) GRM4CYP17A1CYP1A2CYP19A1DHODH
SCHEMBL18174732 0.86 CYP2A6 (0.49) CYP2A6PIM1GRM4KDM4EMEN1
SCHEMBL15161090 0.84 CYP2A6 (0.61) CYP3A4CYP2A6PIM1CYP11B1CYP11B2
SCHEMBL18174562 0.83 CYP3A4 (0.51) CYP3A4CYP2A6PIM1CYP11B1CYP11B2
SCHEMBL18174753 0.83 PIK3CA (0.45) GRM4KDM4EMEN1ALDH1A1LMNA
SCHEMBL18174736 0.82 CYP2A6 (0.48) CYP2A6GRM4CYP17A1CYP1A2CYP19A1
SCHEMBL15161102 0.82 GRM4 (0.46) CYP11B1GRM4CYP17A1CYP1A2CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed