SCHEMBL18174767

SCHEMBL18174767

Cc1ccc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5ccncc5C)c5ccccc45)c4ccccc34)cc2)cn1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 1/20 0.36
CYP19A1 P11511 1/20 0.35
SLC22A12 Q96S37 2/20 0.35
PDK2 Q15119 1/20 0.33
CYP17A1 P05093 3/20 0.33
CYP1A2 P05177 2/20 0.33
S1PR1 P21453 1/20 0.33
S1PR3 Q99500 1/20 0.33
DHODH Q02127 1/20 0.33
PIK3CA P42336 1/20 0.33
HPGDS O60760 1/20 0.33
PIK3C3 Q8NEB9 1/20 0.32
MAPK1 P28482 1/20 0.32
NPC1 O15118 1/20 0.32
PKM P14618 1/20 0.32
RAB9A P51151 1/20 0.32
USP1 O94782 2/20 0.32
WDR48 Q8TAF3 2/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174648 0.91 GRM4 (0.41) GRM4CYP19A1SLC22A12PDK2CYP17A1
SCHEMBL18174761 0.90 GRM4 (0.39) GRM4CYP19A1SLC22A12PDK2CYP17A1
SCHEMBL18174792 0.90 CYP17A1 (0.41) SLC22A12CYP17A1CYP1A2DHODHHPGDS
SCHEMBL18174776 0.86 GRM4 (0.43) GRM4CYP19A1SLC22A12CYP17A1CYP1A2
SCHEMBL18174754 0.85 PIK3CA (0.40) SLC22A12PDK2PIK3CAHPGDSMAPK1
SCHEMBL18174779 0.85 DYRK1A (0.41) PDK2PIK3CAPIK3C3
SCHEMBL15161068 0.85 GRM4 (0.37) GRM4CYP19A1SLC22A12PDK2CYP17A1
SCHEMBL18174793 0.84 CYP11B1 (0.42) CYP19A1CYP1A2DHODHPIK3CA
SCHEMBL18174794 0.84 DHODH (0.42) GRM4CYP19A1CYP17A1CYP1A2S1PR1
SCHEMBL18174772 0.83 PDK2 (0.42) PDK2DHODHPIK3CAHPGDSNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed