SCHEMBL18174792

SCHEMBL18174792

Cc1ccc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5cnccc5C)c5ccccc45)c4ccccc34)cc2)cn1

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 17/20 0.41
CYP1A2 P05177 16/20 0.41
DHODH Q02127 1/20 0.40
SLC22A12 Q96S37 1/20 0.38
HPGDS O60760 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174661 0.91 DHODH (0.44) CYP17A1CYP1A2DHODHSLC22A12
SCHEMBL18174767 0.90 GRM4 (0.36) CYP17A1CYP1A2DHODHSLC22A12HPGDS
SCHEMBL18174771 0.90 DHODH (0.47) CYP17A1CYP1A2DHODHSLC22A12
SCHEMBL18174788 0.86 DHODH (0.50) CYP17A1CYP1A2DHODH
SCHEMBL18174754 0.85 PIK3CA (0.40) SLC22A12HPGDS
SCHEMBL18174780 0.85 CYP17A1 (0.42) CYP17A1CYP1A2DHODH
SCHEMBL10017304 0.85 CYP17A1 (0.53) CYP17A1CYP1A2DHODHSLC22A12
SCHEMBL18174793 0.84 CYP11B1 (0.42) CYP1A2DHODH
SCHEMBL18174797 0.84 CYP17A1 (0.45) CYP17A1CYP1A2DHODH
SCHEMBL18174772 0.83 PDK2 (0.42) DHODHHPGDS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed