Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | AHR | P35869 | 2/20 | 0.44 |
| ▸ | TBK1 | Q9UHD2 | 4/20 | 0.41 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25813452 | 0.97 | KMT2A (0.49) | KMT2AMEN1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL23616431 | 0.88 | AHR (0.47) | KMT2AMEN1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL1635678 | 0.86 | TBK1 (0.45) | SMN1; SMN2NPC1ALDH1A1RAB9ATBK1 | |
| SCHEMBL1365790 | 0.85 | MAPT (0.45) | KMT2AMEN1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL1636789 | 0.84 | TBK1 (0.44) | SMN1; SMN2NPC1ALDH1A1RAB9ATBK1 | |
| SCHEMBL23680290 | 0.82 | KMT2A (0.42) | KMT2AMEN1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL16810129 | 0.82 | BACE1 (0.40) | KMT2AMEN1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL26634503 | 0.80 | KDM4E (0.40) | KMT2AMEN1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL25684796 | 0.80 | KMT2A (0.39) | KMT2AMEN1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL25685245 | 0.80 | KMT2A (0.39) | KMT2AMEN1SMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022034046-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2022-02-17 | — | — | WO | disclosed |
| US-9478758-B1 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2016-10-25 | — | — | US | disclosed |