Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 3/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15158576 | 0.77 | PPARG (0.42) | CAPN1PPARGMAPTFFAR1PPARA | |
| SCHEMBL15158700 | 0.74 | PPARG (0.40) | CAPN1PPARGMAPTFFAR1PPARA | |
| Glitazone SCHEMBL623021 | 0.74 | MAPT (0.73) | PPARGMAPTFFAR1PPARAKMT2A | |
| SCHEMBL15158584 | 0.73 | MAPT (0.38) | CAPN1PPARGMAPTFFAR1KMT2A | |
| SCHEMBL15158582 | 0.73 | PPARG (0.39) | CAPN1PPARGMAPTFFAR1PPARA | |
| SCHEMBL15160009 | 0.73 | PPARG (0.39) | CAPN1PPARGMAPTFFAR1PPARA | |
| SCHEMBL15160008 | 0.73 | PPARG (0.39) | CAPN1PPARGMAPTFFAR1PPARA | |
| SCHEMBL21263121 | 0.72 | ALDH1A1 (0.41) | MAPTKMT2AMEN1CA2 | |
| SCHEMBL15180375 | 0.69 | CAPN1 (0.45) | CAPN1PPARGMAPTFFAR1PPARA | |
| SCHEMBL5213619 | 0.67 | MAOB (0.71) | CAPN1PPARGMAPTFFAR1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560956-B1 | NOVEL SYNTHESIS FOR THIAZOLIDINEDIONE COMPOUNDS | OCTETA THERAPEUTICS LLC (US) | 2016-10-26 | — | — | EP | disclosed |