⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22231070 | 1.00 | — | — | |
| SCHEMBL31619039 | 1.00 | — | — | |
| SCHEMBL22232633 | 0.73 | — | — | |
| SCHEMBL22230976 | 0.73 | — | — | |
| SCHEMBL4259095 | 0.70 | FFAR3 (0.30) | — | |
| SCHEMBL22230897 | 0.70 | FFAR3 (0.30) | — | |
| SCHEMBL22230898 | 0.70 | FFAR3 (0.30) | — | |
| SCHEMBL22252018 | 0.69 | NLRP3 (0.32) | — | |
| SCHEMBL19144137 | 0.67 | — | — | |
| SCHEMBL24576673 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113474333-B | Novel substituted sulphones ureide derivatives | 载度思生命科学有限公司 | 2025-06-13 | — | — | CN | disclosed |
| EP-3405477-B1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2023-06-07 | — | — | EP | disclosed |
| WO-2021254919-A1 | SELECTIVE TMPRSS2 INHIBITORS AND MEDICAL USE THEREOF | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2021-12-23 | — | — | WO | disclosed |
| EP-3911631-A1 | NOVEL SUBSTITUTED SULFONYLUREA DERIVATIVES | Cadila Healthcare Limited (IN) | 2021-11-24 | — | — | EP | disclosed |
| US-11072634-B2 | Inhibitors of transglutaminases | ZEDIRA GMBH (DE) | 2021-07-27 | — | — | US | disclosed |
| US-20210147478-A1 | INHIBITORS OF BLOOD COAGULATION FACTOR XIII | ZEDIRA GMBH (DE) | 2021-05-20 | — | — | US | disclosed |
| WO-2020148619-A1 | NOVEL SUBSTITUTED SULFONYLUREA DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2020-07-23 | — | — | WO | disclosed |
| WO-2019201432-A1 | INHIBITORS OF BLOOD COAGULATION FACTOR XIII | ZEDIRA GMBH (DE) | 2019-10-24 | — | — | WO | disclosed |
| US-20190322700-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2019-10-24 | — | — | US | disclosed |
| WO-2018122419-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2018-07-05 | — | — | WO | disclosed |
| EP-3342779-A1 | INHIBITORS OF TRANSGLUTAMINASES | Zedira GmbH (DE) | 2018-07-04 | — | — | EP | disclosed |
| EP-2788349-B1 | KINASE INHIBITORS | CHIESI FARMA SPA (IT) | 2016-10-26 | — | — | EP | disclosed |