Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 14/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18167147 | 0.77 | PIK3CG (0.39) | MAPTPIK3CGPIK3CDKMT2A | |
| SCHEMBL2732047 | 0.76 | PIK3CD (0.67) | PIK3CGPIK3CD | |
| SCHEMBL18167148 | 0.76 | MAPT (0.38) | MAPTPIK3CGPIK3CDKMT2A | |
| SCHEMBL4285724 | 0.72 | PIK3CG (0.66) | PIK3CG | |
| SCHEMBL15193717 | 0.70 | MEN1 (0.34) | MAPTPIK3CGKMT2A | |
| SCHEMBL15193113 | 0.70 | PIK3CG (0.62) | MAPTPIK3CGPIK3CDKMT2A | |
| SCHEMBL4287398 | 0.70 | PIK3CG (0.53) | MAPTPIK3CG | |
| SCHEMBL4288292 | 0.70 | PIK3CG (0.59) | MAPTPIK3CGPIK3CD | |
| SCHEMBL2721509 | 0.70 | PIK3CG (0.55) | MAPTPIK3CGPIK3CDKMT2A | |
| SCHEMBL4294735 | 0.69 | PIK3CG (0.52) | MAPTPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2630129-B1 | QUINOXALINE DERIVATES | MERCK PATENT GMBH (DE) | 2016-10-26 | — | — | EP | disclosed |