Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 17/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4292830 | 0.93 | PIK3CG (0.51) | PIK3CGPIK3CD | |
| SCHEMBL15199261 | 0.90 | PIK3CG (0.47) | PIK3CGPIK3CDMAPT | |
| SCHEMBL4285883 | 0.88 | PIK3CD (0.54) | PIK3CGPIK3CDMAPT | |
| SCHEMBL18175009 | 0.83 | PIK3CG (0.47) | PIK3CGPIK3CD | |
| SCHEMBL15194173 | 0.83 | PIK3CG (0.48) | PIK3CGPIK3CD | |
| SCHEMBL15199262 | 0.82 | PIK3CG (0.40) | PIK3CGPIK3CD | |
| SCHEMBL2732860 | 0.82 | PIK3CG (0.54) | PIK3CGPIK3CD | |
| SCHEMBL4292331 | 0.81 | PIK3CD (0.53) | PIK3CGPIK3CDMAPT | |
| SCHEMBL2722409 | 0.80 | PIK3CG (0.50) | PIK3CGPIK3CDMAPT | |
| SCHEMBL4294501 | 0.80 | PIK3CG (0.48) | PIK3CGPIK3CDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2630129-B1 | QUINOXALINE DERIVATES | MERCK PATENT GMBH (DE) | 2016-10-26 | — | — | EP | disclosed |