Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 16/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4292331 | 0.89 | PIK3CD (0.53) | PIK3CDPIK3CGMAPTKMT2A | |
| SCHEMBL18175028 | 0.88 | PIK3CG (0.51) | PIK3CDPIK3CGMAPT | |
| SCHEMBL4292830 | 0.87 | PIK3CG (0.51) | PIK3CDPIK3CG | |
| SCHEMBL2732860 | 0.85 | PIK3CG (0.54) | PIK3CDPIK3CG | |
| SCHEMBL15199261 | 0.84 | PIK3CG (0.47) | PIK3CDPIK3CGMAPT | |
| SCHEMBL2722409 | 0.83 | PIK3CG (0.50) | PIK3CDPIK3CGMAPT | |
| SCHEMBL15194173 | 0.83 | PIK3CG (0.48) | PIK3CDPIK3CG | |
| SCHEMBL4288277 | 0.82 | PIK3CD (0.57) | PIK3CDPIK3CGMAPTKMT2A | |
| SCHEMBL4297407 | 0.82 | PIK3CD (0.50) | PIK3CDPIK3CGMAPTKMT2A | |
| SCHEMBL4290396 | 0.82 | PIK3CD (0.50) | PIK3CDPIK3CGMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012052102-A1 | QUINOXALINE DERIVATES | MERCK PATENT GMBH (DE) | 2012-04-26 | — | — | WO | disclosed |