Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | F2 | P00734 | 2/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.53 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.53 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.53 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.53 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15075762 | 0.84 | ALDH1A1 (0.51) | ALDH1A1MAPTALOX15L3MBTL1HPGD | |
| SCHEMBL10473358 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPTALOX15L3MBTL1HPGD | |
| SCHEMBL10473279 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPTALOX15L3MBTL1HPGD | |
| SCHEMBL10472249 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPTALOX15L3MBTL1HPGD | |
| SCHEMBL3555044 | 0.77 | F2 (0.85) | ALDH1A1MAPTALOX15L3MBTL1HPGD | |
| SCHEMBL4767629 | 0.77 | NPC1 (0.61) | ALDH1A1MAPTALOX15L3MBTL1HPGD | |
| SCHEMBL4873981 | 0.77 | NPC1 (0.61) | ALDH1A1MAPTALOX15L3MBTL1HPGD | |
| SCHEMBL1397421 | 0.77 | NPC1 (0.61) | ALDH1A1MAPTALOX15L3MBTL1HPGD | |
| SCHEMBL13654718 | 0.75 | ALDH1A1 (0.63) | ALDH1A1MAPTALOX15L3MBTL1HPGD | |
| SCHEMBL8106249 | 0.75 | F2 (0.89) | ALDH1A1MAPTALOX15L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170309-B1 | 2,6-DIOXO,-2,3-DIHYDRO-1H-PURINE COMPOUNDS USEFUL FOR TREATING DISORDERS RELATED TO THE ACTIVITY OF THE TRPA1 CHANNEL | HYDRA BIOSCIENCES INC (US) | 2016-10-26 | — | — | EP | disclosed |