Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.69 |
| ▸ | TP53 | P04637 | 3/20 | 0.69 |
| ▸ | KDM1A | O60341 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18176018 | 0.86 | MEN1 (0.72) | MEN1KMT2AGAAALDH1A1ALOX15 | |
| SCHEMBL8556554 | 0.86 | KMT2A (0.75) | MEN1KMT2AGAAALDH1A1ALOX15 | |
| SCHEMBL7348805 | 0.83 | MEN1 (0.71) | MEN1KMT2AGAAALDH1A1ALOX15 | |
| SCHEMBL2175908 | 0.82 | RAB9A (0.77) | MEN1KMT2AGAAALDH1A1ALOX15 | |
| SCHEMBL12852615 | 0.82 | MEN1 (0.73) | MEN1KMT2AGAAALDH1A1ALOX15 | |
| SCHEMBL20888451 | 0.81 | MEN1 (0.72) | MEN1KMT2AGAAALDH1A1ALOX15 | |
| SCHEMBL1353749 | 0.80 | SMN1; SMN2 (0.60) | MEN1KMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL17712431 | 0.79 | SMN1; SMN2 (0.71) | MEN1KMT2AGAAALDH1A1ALOX15 | |
| SCHEMBL17011812 | 0.79 | KDM1A (1.00) | MEN1KMT2AGAAALDH1A1ALOX15 | |
| Hydrochloric Acid SCHEMBL17003193 | 0.78 | KDM1A (0.98) | MEN1KMT2AGAAALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417120-B1 | SUBSTITUTED PIPERIDINES AS CCR3 ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2016-10-26 | — | — | EP | disclosed |