Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3283890 | 1.00 | KCNA5 (0.52) | KCNA5SMN1; SMN2MEN1GAAKMT2A | |
| Hydrochloric Acid SCHEMBL3283896 | 0.98 | KCNA5 (0.51) | KCNA5SMN1; SMN2MEN1GAAKMT2A | |
| Hydrochloric Acid SCHEMBL3283886 | 0.98 | KCNA5 (0.51) | KCNA5SMN1; SMN2MEN1GAAKMT2A | |
| SCHEMBL1051978 | 0.86 | SMN1; SMN2 (0.41) | KCNA5SMN1; SMN2MEN1GAAKMT2A | |
| SCHEMBL1077616 | 0.85 | SMN1; SMN2 (0.55) | KCNA5SMN1; SMN2MEN1GAAKMT2A | |
| SCHEMBL1051991 | 0.85 | SMN1; SMN2 (0.55) | KCNA5SMN1; SMN2MEN1GAAKMT2A | |
| Hydrochloric Acid SCHEMBL5742023 | 0.84 | SMN1; SMN2 (0.53) | KCNA5SMN1; SMN2MEN1GAAKMT2A | |
| Hydrochloric Acid SCHEMBL7321879 | 0.84 | SMN1; SMN2 (0.53) | KCNA5SMN1; SMN2MEN1GAAKMT2A | |
| SCHEMBL30915255 | 0.84 | CYP2C19 (0.42) | KCNA5SMN1; SMN2MEN1GAAKMT2A | |
| SCHEMBL19410196 | 0.84 | CYP2C19 (0.42) | KCNA5SMN1; SMN2MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417120-B1 | SUBSTITUTED PIPERIDINES AS CCR3 ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2016-10-26 | — | — | EP | disclosed |